CAPSULE NO & THEIR APPROXIMATE CAPACITY IN mg & ml
|
000 -950 - 1.37
00 -650 - 0.95
0 - 450 - 0.68
1 - 300 - 0.50
2 - 250 - 0.37
3 - 200 - 0.30
4 - 150 - 0.21
5 - 100 - 0.13
|
PROPORTIONS REQUIRED FOR A PRIMARY
EMULSION
|
(oil:water:gum)
Fixed oils :- 4:2:1
Volatile oils:- 2:2:1
Mineral oils:- 3:2:1
Oleoresins:-1:2:1
|
CODE: LPSO ( apply
this for tweens & spans)
|
for eg ..
spans 20 mean sorbitan mono laurate
tween 80 mean
Polyoxyethylene sorbitan monooleate
L :Laurate - 20
P : Palmitate - 40
S: Stearate - 60
O: Oleate - 80
|
SOLUBILITY
|
DESCRIPTIVE
TERM - APPROX VOL OF SOLVENT IN ml/gm OF SOLUTE
Verysoluble - less than 1
Freely soluble - 1 - 10
Soluble- 10 - 30
Sparingly soluble - 30 - 100
Slightly soluble - 100 - 1000
Very slightly soluble - 1000 - 10,000
Practically insoluble - more than 10,000
|
STORAGE TEMPERATURE
|
Cold - 2 - 8 degree centi
Cool - 8 - 25
Room - temp prevailing in the working area
Warm -between 30 - 40
Excessive heat - > 40 degree
|
SUCROSE BASED DILUANTS
Dipac - 97 % sucrose + 3% moddified dextrose
Nutab - 95 % sucrose +
4 % invert sugar
Sugar tab - 90 - 93 %
sucrose + 7 - 10 % invert sugar
Compressibility index / carrs
index = tapped density - bulk density / tapped density
hausners ratio = tapped density /
bulk density
|
ANGLE OF
REPOSE FLOW
CHARACTER
25 - 30 - Excellent
31 - 35 - Good
36 - 40 - Fair
41 - 45 - Passable
46 - 55 - poor
56 - 65 - Very poor
>66 - very very poor
|
Types of Glass used in
Pharmaceutical Industries
Parenteral Use
Type I Glass:
Highly Resistant Borosillicate.
Used for Buffered and Unbuffered
aqueous solution.
Type II Glas:
Highly Resistant Sodalime glass.
Buffered aqueous solution below pH
7.0
Type III Glass:
Moderately Resistant Sodalime
glass.
Used for dry powder and oily
solution.
Non-Parenteral Use
Type IV Glass:
General Purpose Sodalime glass.
Not for parenteral, for tablet,liquid oral and externals.
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